Update on liver disease for the nephrologist: From primary diseases involving the liver & kidney to Extracorporeal Therapies

Saturday, April 29, 2023

2:00 PM – 3:30 PM ET

Location: Convention Center: 201

CE: Live CME: 1.50

Selected By: ASPN Independent

Chair(s)

Tennille Webb, MD, MSPH

Assistant Professor
University of Alabama at Birmingham/Children’s of Alabama
Birmingham, Alabama, United States

Moderator(s)

Katherine Dell, MD (she/her/hers)

Vice Chair of Research, Pediatric Institute Professor of Pediatrics
Cleveland Clinic Children's and Case Western Reserve University
Cleveland, Ohio, United States

Disclosure(s):

Tennille N. Webb, MD, MSPH: I do not have any relevant financial / non-financial relationships with any proprietary interests.

Katherine M. Dell, MD: AMAG (Ongoing) (Products/Services: Advisory Committee); Amgen (Ongoing) (Products/Services: Research Support including clinical trials & the principal or named investigator); Otsuka (Ongoing) (Products/Services: Research Support including clinical trials & the principal or named investigator); Travere (Ongoing) (Products/Services: Research Support including clinical trials & the principal or named investigator); UptoDate (Ongoing) (Products/Services: Intellectual Property including patent beneficiary and royalties)

Session

Description: Brief Description of Overall Session: This session will seek to review the complex interactions between liver and kidney disease. The session will begin with an overview and update of primary diseases that impact the liver and kidney. The session will then transition into the short-term and long-term management of children with liver disease from a nephrologist’s perspective including: AKI, hepatorenal syndrome, extracorporeal therapies for acute liver failure, and managing children after liver transplant.

1. Topic/title: An update on diseases that impact the kidneys and liver

Objective: Understand new advancements in the pathophysiology, diagnosis, and management of hepatorenal diseases

2. Topic/title: Acute kidney injury and hepatorenal syndrome in children with liver disease

Objective: Understand the epidemiology and risk factors for AKI in children with liver disease, understand management of AKI in pediatric liver disease including therapies for hepatorenal syndrome

3. Topic/title: Extracorporeal therapies for the management of acute liver failure

Objective: Understand the indications and efficacy of extracorporeal liver support systems (CRRT, MARS, plasmapheresis)

4. Managing patients with liver transplant: From the OR to CKD

Objective: Review kidney related complications and management throughout the course of liver transplantation

Learning Objectives:

1. Recognize kidney complications of acute liver failure and other diseases that impact both kidney and liver.
2. Describe management of acute liver failure with extracorporeal therapies.
3. Understand long term kidney complications of liver transplant.

Presentations:

2:00 PM – 2:20 PM ET

An update on diseases that impact the kidneys and liver
Speaker: Erum A. Hartung, MD, MTR – Children's Hospital of Philadelphia
2:20 PM – 2:40 PM ET

Acute kidney injury and hepatorenal syndrome in children with liver disease
Speaker: Jun Oh, PhD (he/him/his) – University of Hamburg
2:40 PM – 3:00 PM ET

Extracorporeal therapies for the management of acute liver failure
Speaker: Ayse Akcan Arikan, MD (she/her/hers) – Baylor College of Medicine
3:00 PM – 3:20 PM ET

Managing patients with liver transplant: From the OR to CKD
Speaker: Rebecca Ruebner, MD, MSCE – Johns Hopkins University