Personalized medicine: how your patient’s biology transcends “race"

Sunday, April 30, 2023

2:00 PM – 3:30 PM ET

Location: Convention Center: 150 A

CE: Live CME: 1.50

Selected By: SPR
Co-sponsored By: AAP SoNPM, Endo

Chair(s)

Danielle Ahn, MD

Assistant Professor
Columbia University Medical Ce
New York, New York, United States
Joshua Motelow, MD, PhD (he/him/his)

Assistant Professor
Columbia University Vagelos College of Physicians and Surgeons
New York, New York, United States

Disclosure(s):

Danielle Ahn, MD: No financial relationships to disclose

Joshua E. Motelow, MD, PhD: No financial relationships to disclose

Session

Description: Approaching the care of critically ill children with precision medicine techniques challenges the practice of using race as a reliable proxy for biological differences. Genomic approaches in the diagnosis and prognostication of pediatric patients are more accessible and less cost prohibitive, making it possible to use these modalities to remove race as an essential consideration in diagnostic algorithms and clinical practice guidelines. This session explores the methodologies that counter the current paradigm of race as a biological variable, while also highlighting the biases that persist in these diagnostic approaches.

Learning Objectives:

Explore how precision medicine methodologies are helping to characterize host risk factors in major disease entities.
Show that inter- and intra-racial differences found in precision medicine approaches do not support race as a legitimate biologic variable.
Identify considerations for enrolling genomics research participants from diverse backgrounds and how the representation of minority populations in reference datasets influences diagnostic accuracy.

Presentations:

2:00 PM – 2:10 PM ET

Introduction
Speaker: Danielle Ahn, MD – Columbia University Medical Ce
2:10 PM – 2:30 PM ET

E-racing bias when prognosticating outcomes in sepsis and ARDS
Speaker: Nadir Yehya, MD MSCE – Children's Hospital of Philadelphia
2:30 PM – 2:50 PM ET

Assessing risk factors for AKI and renal failure using biomarkers.
Speaker: Stuart L. Goldstein, MD (he/him/his) – Cincinnati Children's Hospital
2:50 PM – 3:10 PM ET

Enrolling diverse populations in newborn genomics research
Speaker: Stacey Pereira, PhD (she/her/hers) – Baylor College of Medicine
3:25 PM – 3:30 PM ET

Closing remarks, Q&A
Speaker: Joshua E. Motelow, MD, PhD (he/him/his) – Columbia University Vagelos College of Physicians and Surgeons