Assembling a Multidisciplinary Team for Implementation of Pharmacogenetic Testing in Pediatrics

Friday, April 28, 2023

3:45 PM – 5:15 PM ET

Location: Convention Center: 203 AB

CE: Live CME: 1.50

Selected By: CHTRC
Co-sponsored By: SDBP

Chair(s)

Sonya Tang Girdwood, MD, PhD (she/her/hers)

Assistant Professor of Pediatrics
Pediatrics
Cincinnati Children' Hospital Medical Center
Cincinnati, Ohio, United States
Laura Ramsey, PhD

Assistant Professor
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States

Disclosure(s):

Sonya C. Tang Girdwood, MD, PhD: I do not have any relevant financial / non-financial relationships with any proprietary interests.

Laura B. Ramsey, PhD: BTG Specialty Pharmaceuticals: Consultant (Ongoing), Research Support including clinical trials & the principal or named investigator (Ongoing)

Session

Description: Pharmacogenetics is a critical component of precision medicine and evidence for incorporating pharmacogenetics into clinical practice in pediatrics is growing rapidly. Many institutions are interested in the implementation of pharmacogenetic testing but may not know which of the different models of implementation to use or which key stakeholders to include. In this session, we will provide an introduction to pharmacogenetics and the types of available pharmacogenetic tests in pediatrics (e.g. single gene testing, multigene testing, or sequencing-based tests). Then, three different speakers with various training backgrounds will discuss their institutions’ models of implementing pharmacogenetic testing and how their roles are critical to the success of their pharmacogenetics services: 1) A pharmacist will discuss her role in outpatient primary care and subspecialty clinics where pharmacogenetic testing is implemented. 2) A clinician will describe her role in the GOLDILOKS inpatient consult service that provides dose individualization and clinical optimization using pharmacogenetic testing and other individual factors in hospitalized children. 3) A clinical pharmacologist will describe her role in a pharmacogenetic service that provides testing for all children admitted to the inpatient psychiatry unit with pre-defined recommendation templates for clinicians. The remaining 20 minutes of the session will be Q&A, moderated by a pediatric hospitalist and clinical pharmacologist, to allow audience members to learn more about the different types of models of pharmacogenetic implementation. By the end of the session, participants should recognize that a multidisciplinary team that includes bedside clinicians, pharmacists, and pharmacologists, is needed for successful implementation of pharmacogenetic testing.

Learning Objectives:

Distinguish among types of available pharmacogenetics testing options
Differentiate between models of pharmacogenetic testing and interpretation, including testing in outpatient clinics, use of an inpatient consult service, and routine inpatient testing
Describe the benefits of having multidisciplinary team members, including bedside clinicians, pharmacists, and pharmacologists, in the implementation of pharmacogenetic testing

Presentations:

3:45 PM – 4:15 PM ET

Introduction to Pharmacogenetics and the Different Types of Pharmacogenetic Tests (10 min); Q&A Session (20 min at end)
Speaker: Sonya C. Tang Girdwood, MD, PhD (she/her/hers) – Cincinnati Children' Hospital Medical Center
4:15 PM – 4:35 PM ET

The Role of a Pharmacist in Implementing Pharmacogenetic Testing in Outpatient Clinics
Speaker: Kristin Wiisanen, PharmD (she/her/hers) – University of Florida College of Pharmacy
4:35 PM – 4:55 PM ET

The Role of a Bedside Clinician in an Inpatient Consult Service Utilizing Pharmacogenetic Testing
Speaker: Stephani Stancil, PhD, APRN (she/her/hers) – Children's Mercy Hospitals and Clinics
4:55 PM – 5:15 PM ET

The Role of a Clinical Pharmacologist in a Pharmacogenetics Service with Routine Inpatient Testing
Speaker: Laura B. Ramsey, PhD – Cincinnati Children's Hospital Medical Center