PAS Postgraduate Course: Neonatal Acute Kidney Injury (AKI): From Basic and Clinical Science to Caring for Baby (and their beans) in the crib.

Friday, April 28, 2023

7:00 AM – 1:30 PM ET

Chair(s)

Alison Kent, BMBS, FRACP, MD

Adjunct Professor of Pediatrics
University of Rochester School of Medicine and Dentistry
Rochester, New York, United States
Meredith Schuh, MD (she/her/hers)

Assistant Professor
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
JS

Jeffrey Segar, MD (he/him/his)

Professor
Medical College of Wisconsin
Milwaukee, Wisconsin, United States
KS

Keia Sanderson, MD, MSc

Assistant Professor of Medicine and Pediatrics
Medicine-Nephrology
University of North Carolina at Chapel Hill School of Medicine
Chapel Hill, North Carolina, United States

Disclosure(s):

Alison Kent, BMBS, FRACP, MD: No financial relationships to disclose

Meredith P. Schuh, MD: Otsuka (Ongoing) (Products/Services: Research Support including clinical trials & the principal or named investigator)

Jeffrey Segar, MD: Pfizer (Ongoing) (Products/Services: Ownership Interest including individual stocks, stock options, excluding diversified mutual funds)

Keia Sanderson, MD, MSc: No financial relationships to disclose

Session

Description: The course will cover basic, translational, and clinical science from fetal physiology to post-discharge follow-up for neonatal AKI. The course is designed to delivering an overview of current research advances and clinical practice strategies in neonatal AKI, including the use of kidney support therapies in neonates in a variety of settings (ECMO, multiorgan failure, AKI, etc.) The speakers will aim to help foster ideas for future research, quality improvement projects, and improved care.

Learning Objectives:

Upon completion, participants will understand neonatal kidney function, the pathophysiology of neonatal AKI, impact of prematurity, and long-term implication of neonatal AKI.
Upon completion, participants will understand the definition of neonatal AKI, the risk factors associate with neonatal AKI, and the epidemiology & impact of neonatal AKI.
Learners will be exposed to state-of-the -art topics: novel AKI biomarkers, neonatal ECMO & nephrology (AKI, fluid balance, kidney support therapy (KST)), and neonatal KST.

Presentations:

7:00 AM – 7:35 AM ET

Nephron endowment and its impact on long-term health. The link between prematurity, AKI, and the risk for CKD.
Speaker: Jennifer R. Charlton, MD, MSc (she/her/hers) – University of Virginia
7:35 AM – 8:10 AM ET

Neonatal Kidney Function: What happens before birth, after birth, and when the kidney gets injured?
Speaker: Matthew Harer, MD (he/him/his) – University of Wisconsin School of Medicine and Public Health
8:10 AM – 8:45 AM ET

Pathophysiology of neonatal acute kidney injury: AKI is more than a rise in serum creatinine: it's a multisystem disease.
Speaker: Danielle Soranno, MD (she/her/hers) – Indiana University
8:45 AM – 9:20 AM ET

Can urine biomarkers help us care for neonates? Translational science to identify AKI biomarkers and therapeutic targets.
Speaker: Prasad Devarajan, MD FAAP FASN – University of Cincinnati College of Medicine
10:00 AM – 10:25 AM ET

Acute kidney injury definition, incidence, and outcomes
Speaker: Jennifer Garcia Jetton, MD (she/her/hers) – Medical College of Wisconsin/Children's Wisconsin
10:25 AM – 10:50 AM ET

The impact of fluid balance on outcomes in neonates
Speaker: Michelle C. Starr, MD MPH (she/her/hers) – Indiana University School of Medicine
10:50 AM – 11:15 AM ET

Acute kidney injury, kidney support therapy, and fluid balance management for neonates on extracorporeal membrane oxygenation
Speaker: David Selewski, MD, MSCR – Medical University of South Carolina
12:00 PM – 12:25 PM ET

Care of the neonate with fluid overload and acute kidney injury
Speaker: David Askenazi, MD, MSPH (he/him/his) – University of Alabama at Birmingham
12:25 PM – 12:50 AM ET

Neonatal Kidney support therapy Part 1: the neonatologist perspective
Speaker: Cara L. Slagle, MD (she/her/hers) – Cincinnati Children's Hospital Medical Center
12:50 PM – 1:15 PM ET

Neonatal Kidney support therapy Part 2: the nephrologist perspective
Speaker: Shina Menon, MD (she/her/hers) – University of Washington School of Medicine