Neonatal Infectious Diseases/Immunology
Neonatal Infectious Diseases/Immunology 3
Michelle J. Vaz, MD (she/her/hers)
Assistant Professor of Pediatrics, Attending Neonatologist
Hassenfeld Children's Hospital at NYU Langone
Tenafly, New Jersey, United States
Polysaccharide capsule production enhances GBS GI colonization in vivo. In an A909 genetic background, production of serotype Ia capsule provides a competitive advantage over an isogenic strain producing a type III capsule. The murine model is a valuable tool to understand the role of GBS capsule types in GI colonization and progression to invasive disease.